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Can J Clin Pharmacol Vol 17 (1) Winter 2010:e1-e4; January 4, 2010
Unusual Reactions to 5-HT₃ Receptor Antagonists in a Child with Rhabdomyosarcoma
Case Report

Candace YW Lee, Savithiri Ratnapalan, Margaret Thompson, Paul C Nathan, Jordan Closs, Amy French, Angela Punnett, Facundo Garcia-Bournissen, Shinya Ito, Gideon Koren

A case of unusual reactions consisting of involuntary abnormal facial movements in a child following exposure to the 5-HT₃ receptor antagonists for prophylaxis against chemotherapy-induced vomiting is presented. Potential mechanisms for these reactions are discussed. 

Key Words: 5-HT₃ receptor, antagonists, child

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• Canadian Society of Pharmacology and Therapeutics
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